Niendorf/Seeliger and Hoff merge three disciplines - MRI technology, parametric MRI, quantitative physiological techniques and clinical nephrology - to study renal hemodynamics and oxygenation under physiologic conditions and in AKI. As a team, all three share the expertise and success acquired with the MR-PHYSIOL setup accomplished during the 1st funding period. Niendorf is a MR physicist, Chair for Ultrahigh Field MR at the Charité, and is the head of the Berlin Ultrahigh Field Facility (B.U.F.F. MDC Campus Berlin-Buch). This facility houses, among other, a 9.4 Tesla small bore MRI scanner for imaging of small rodents. Niendorf focuses on novel methodology of mapping and probing morphology, function, physiology and metabolism and its application to advance renal MRI. Seeliger, who heads the working group “Integrative Kidney Physiology” at the Charité Institute of vegetative physiology, provides expertise in integrative physiology techniques (see Project 3). Hoff is a junior faculty member and clinical fellow at the department of nephrology and intensive care medicine. He provides experience in animal models of AKI.
*Dr. Hoff left the institution in October 2016.