The Seeliger/Arakelyan group contributes to the network by expertise in integrative studies on renal hemodynamics and oxygenation. In rat models of AKI, they characterize regulation of renal blood flow, intrarenal perfusion, and oxygenation by use of pathophysiologically relevant test procedures. This group has underscored the importance of medullary hypoperfusion and hypoxia for the development of CI-AKI and renal I/RI. By their work on CI-AKI, the importance of fluid viscosity for this form of AKI became widely accepted.
*Dr. Arakelyan left the institution in December 2014.